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"Whether you are seeking treatment for a particular ailment or a path to greater health, Alternative Medicine offers a wide array of options and therapies-- ones that will fit with your needs, lifestyle and personal outlook. Unlike conventional pharmaceutical medicine, there is no 'one size fits all' approach with alternative medicine; let this book be your guide."--Back cover.

Up to 50% of individuals with major depressive disorder (MDD) do not recover after two antidepressant medication trials, and therefore meet the criteria for treatment-resistant depression (TRD). Mindfulness-based cognitive therapy (MBCT) is one promising treatment; however, the extent to which MBCT influences clinical outcomes relative to baseline neural activation remains unknown. In the present study we investigated baseline differences in amygdala activation between TRD patients and healthy controls (HCs), related amygdala activation to depression symptoms, and examined the impacts of MBCT and amygdala activation on longitudinal depression outcomes. At baseline, TRD patients (n = 80) and HCs (n = 37) participated in a functional magnetic resonance imaging task in which they identified either the emotion (affect labeling) or the gender (gender labeling) of faces, or passively viewed faces (observing). The TRD participants then completed eight weeks of MBCT or a health enhancement program (HEP). Relative to HCs, the TRD patients demonstrated less amygdala activation during affect labeling, and marginally less during gender labeling. Blunted amygdala activation in TRD patients during affect labeling was associated with greater depression severity. MBCT was associated with greater depression reductions than was HEP directly following treatment; however, at 52 weeks the treatment effect was not significant, and baseline amygdala activation across the task conditions predicted depression severity in both groups. TRD patients have blunted amygdala responses during affect labeling that are associated with greater concurrent depression. Furthermore, although MBCT produced greater short-term improvements in depression than did HEP, overall baseline amygdala reactivity was predictive of long-term clinical outcomes in both groups.

Up to 50% of individuals with major depressive disorder (MDD) do not recover after two antidepressant medication trials, and therefore meet the criteria for treatment-resistant depression (TRD). Mindfulness-based cognitive therapy (MBCT) is one promising treatment; however, the extent to which MBCT influences clinical outcomes relative to baseline neural activation remains unknown. In the present study we investigated baseline differences in amygdala activation between TRD patients and healthy controls (HCs), related amygdala activation to depression symptoms, and examined the impacts of MBCT and amygdala activation on longitudinal depression outcomes. At baseline, TRD patients (n = 80) and HCs (n = 37) participated in a functional magnetic resonance imaging task in which they identified either the emotion (affect labeling) or the gender (gender labeling) of faces, or passively viewed faces (observing). The TRD participants then completed eight weeks of MBCT or a health enhancement program (HEP). Relative to HCs, the TRD patients demonstrated less amygdala activation during affect labeling, and marginally less during gender labeling. Blunted amygdala activation in TRD patients during affect labeling was associated with greater depression severity. MBCT was associated with greater depression reductions than was HEP directly following treatment; however, at 52 weeks the treatment effect was not significant, and baseline amygdala activation across the task conditions predicted depression severity in both groups. TRD patients have blunted amygdala responses during affect labeling that are associated with greater concurrent depression. Furthermore, although MBCT produced greater short-term improvements in depression than did HEP, overall baseline amygdala reactivity was predictive of long-term clinical outcomes in both groups.

Cancer is the uncontrolled growth of cells, which damages healthy tissue and causes disease. The American Cancer Society differentiates more than 100 types of cancers that manifest in diverse ways throughout the human body. Treatment of cancer can vary from local to systemic and from mildly invasive to radical depending on the type of cancer and the extent of disease.

Fragile X syndrome (FX), the most common heritable cause of mental retardation and autism, is a developmental disorder characterized by physical, cognitive, and behavioral deficits. FX results from a trinucleotide expansion mutation in the fmr1 gene that reduces levels of fragile X mental retardation protein (FMRP). Although research efforts have focused on FMRP's impact on mGluR signaling, how the loss of FMRP leads to the individual symptoms of FX is not known. Previous studies on human FX blood cells revealed alterations in the cyclic adenosine 3′, 5′-monophosphate (cAMP) cascade. We tested the hypothesis that cAMP signaling is altered in the FX nervous system using three different model systems. Induced levels of cAMP in platelets and in brains of fmr1 knockout mice are substantially reduced. Cyclic AMP induction is also significantly reduced in human FX neural cells. Furthermore, cAMP production is decreased in the heads of FX Drosophila and this defect can be rescued by reintroduction of the dfmr gene. Our results indicate that a robust defect in cAMP production in FX is conserved across species and suggest that cAMP metabolism may serve as a useful biomarker in the human disease population. Reduced cAMP induction has implications for the underlying causes of FX and autism spectrum disorders. Pharmacological agents known to modulate the cAMP cascade may be therapeutic in FX patients and can be tested in these models, thus supplementing current efforts centered on mGluR signaling.
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Background: A growing literature describes the importance of social-emotional learning (SEL) for student social behavior, academic performance, and emotional health. One widely implemented school program, the Quiet Time program, has been shown to improve factors associated with SEL, including positive emotional and behavioral coping skills, resilience, and self-actualization. Methods: A total of 101 sixth-grade students, 51 students from a public West Coast Quiet Time school practicing Transcendental Meditation (TM) and 50 non-meditating students from a matched-control school, participated in the study. Both teacher rating of social-emotional competencies, using the Devereux Student Strengths Assessment (DESSA), and student self-reported psychological distress, using the Strengths and Difficulties Questionnaire (SDQ) emotional symptoms scale, were completed at baseline and four-month posttest. Results: Significant improvement was found in the TM group compared to controls in social-emotional competencies for both the entire sample and high-risk subgroup (p values <.001; effect sizes = .78 and 1.32, respectively). A decrease in negative emotional symptoms was observed in high-risk TM students compared to controls (p < .073; effect size = -.70). Conclusion: These findings indicate the value of implementing TM to enhance social-emotional learning and decrease psychological distress in middle school students. Future studies are encouraged. [ABSTRACT FROM AUTHOR]; Copyright of Education is the property of Project Innovation, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

History was made when the United Nations published Transforming Our World: The 2030 Agenda for Sustainable Development and world leaders stepped up to pledge unifying commitments to secure a sustainable future "where all life can thrive." Now, we the people—the world's individuals, organizations, and communities that have been championing the shared vision of a sustainable future—need access to the best leadership guidance available to build on the successes of past efforts and advance breakthrough progress.  Evolving Leadership for Collective Wellbeing: Lessons for Implementing the United Nations Sustainable Development Goals provides that guidance. This collection is a go-to resource for individuals wishing to heighten leadership effectiveness through access to vanguard theory and practice. It highlights stories and insights from leadership practitioners and scholars around the world, in the process offering invaluable insights into diverse lessons, models, and practices, and it offers case and place-based chapters that bridge theory and practice to empower diverse actors around the world. As the Agenda acknowledges, "The future of humanity and of our planet lies in our hands. ... It will be for all of us to ensure that the journey is successful and its gains irreversible." Evolving Leadership for Collective Wellbeing is essential reading not only for leaders and leadership scholars, but also for anyone eager to face the Agenda’s challenge head on.

OBJECTIVE: This study examined the relative contribution of five dispositional mindfulness (DM) facets and two aspects of social support along with sex in predicting psychological adjustment.PARTICIPANTS: Three hundred fifty-three undergraduates (72% female; M = 18.82 years) participated with data collected from September 2014 through March 2016. METHODS: Self-report measures of DM, social support, perceived stress, and emotional well-being were completed. RESULTS: Sex and higher scores on specific mindfulness facets (ie, nonreactivity, nonjudging) predicted lower stress and greater emotional well-being. Higher family support predicted lower stress, whereas friend support predicted greater emotional well-being. The mindfulness facets were stronger predictors of adjustment than the social support domains. Females reported higher perceived stress and lower emotional well-being than males, and males scored significantly higher on total mindfulness, nonjudging, and nonreactivity. CONCLUSIONS: Results have implications for mindfulness-based interventions with college students such that focusing on the nonjudging and nonreactivity facets may enhance effectiveness.

Effects of interventions for improving mental health of health professional students has not been established. This review analysed interventions to support mental health of health professional students and their effects. The full holdings of Medline, PsycINFO, EBM Reviews, Cinahl Plus, ERIC and EMBASE were searched until 15th April 2016. Inclusion criteria were randomised controlled trials of undergraduate and post graduate health professional students, group interventions to support mental health compared to alternative education, usual curriculum or no intervention; and post-intervention measurements for intervention and control participants of mindfulness, anxiety, depression, stress/distress or burnout. Studies were limited to English and short term effects. Studies were appraised using the PEDro scale. Data were synthesised using meta-analysis. Four comparisons were identified: psychoeducation or cognitive-behavioural interventions compared to alternative education, and mindfulness or relaxation compared to control conditions. Cognitive-behavioural interventions reduced anxiety (−0.26; −0.5 to −0.02), depression (−0.29; −0.52 to −0.05) and stress (0.37; −0.61 to −0.13). Mindfulness strategies reduced stress (−0.60; −0.97 to −0.22) but not anxiety (95% CI −0.21 to 0.18), depression (95% CI −0.36 to 0.03) or burnout (95% CI −0.36 to 0.10). Relaxation strategies reduced anxiety (SMD −0.80; 95% CI −1.03 to −0.58), depression (−0.49; −0.88 to −0.11) and stress (−0.34; −0.67 to −0.01). Method quality was generally poor. Evidence suggests that cognitive-behavioural, relaxation and mindfulness interventions may support health professional student mental health. Further high quality research is warranted.

Mindfulness-based treatments for health issues and psychological disorders have increased in popularity and use. A large amount of empirical evidence indicates that these treatments are effective. However, it is possible that these scientific investigations of mindfulness-based treatments have not been conducted with representative samples. In particular, it seems like most participants in these studies are female. In order to explore this, we conducted a systematic review and examined the sample demographics of 117 articles that investigated the effectiveness of mindfulness-based stress reduction or mindfulness-based cognitive therapy via randomized controlled trials. Male participants accounted for less than 29% of the 9820 total participants. These findings suggest that the evidence supporting the effectiveness of mindfulness-based treatments is based on non-representative samples, and future research should work to correct this.

This book makes the unorthodox claim that there is no such thing as mental health. It also deglamourises nature-based psychotherapies, deconstructs therapeutic landscapes and redefines mental health and wellbeing as an ecological process distributed in the environment....

This book makes the unorthodox claim that there is no such thing as mental health. It also deglamourises nature-based psychotherapies, deconstructs therapeutic landscapes and redefines mental health and wellbeing as an ecological process distributed in the environment....

OBJECTIVE:To examine the relationship between mindfulness and alcohol problems in college students, as well as the role of stress as a mediator in this relationship. PARTICIPANTS: Participants were 310 students from a small, private college in the Northeast. METHODS: Students completed self-report measures, including the Perceived Stress Scale, the Five Facet Mindfulness Questionnaire, and the Rutgers Alcohol Problems Index. RESULTS: Mindfulness was negatively correlated with alcohol problems and stress, whereas stress positively correlated with alcohol problems. Results implicated stress as fully mediating the relationship between mindfulness and alcohol problems. Alcohol problems were negatively correlated with the Acting With Awareness and Describing Experience facets of mindfulness. CONCLUSION: Mindfulness-based stress reduction or other mindfulness programs may be useful in decreasing alcohol problems on college campuses via the effects on stress.

ObjectiveDepressive symptoms are common among patients with fibromyalgia, and behavioral intervention has been recommended as a major treatment component for this illness. The objective of this study was to test the effects of the Mindfulness‐Based Stress Reduction (MBSR) intervention on depressive symptoms in patients with fibromyalgia. Methods This randomized controlled trial examined effects of the 8‐week MBSR intervention on depressive symptoms in 91 women with fibromyalgia who were randomly assigned to treatment (n = 51) or a waiting‐list control group (n = 40). Eligible patients were at least 18 years old, willing to participate in a weekly group, and able to provide physician verification of a fibromyalgia diagnosis. Of 166 eligible participants who responded to local television news publicizing, 49 did not appear for a scheduled intake, 24 enrolled but did not provide baseline data, and 2 were excluded due to severe mental illness, leaving 91 participants. The sample averaged 48 years of age and had 14.7 years of education. The typical participant was white, married, and employed. Patients randomly assigned to treatment received MBSR. Eight weekly 2.5‐hour sessions were led by a licensed clinical psychologist with mindfulness training. Somatic and cognitive symptoms of depression were assessed using the Beck Depression Inventory administered at baseline, immediately postprogram, and at followup 2 months after the conclusion of the intervention. Results Change in depressive symptoms was assessed using slopes analyses of intervention effects over time. Depressive symptoms improved significantly in treatment versus control participants over the 3 assessments. Conclusion This meditation‐based intervention alleviated depressive symptoms among patients with fibromyalgia.

ObjectiveDepressive symptoms are common among patients with fibromyalgia, and behavioral intervention has been recommended as a major treatment component for this illness. The objective of this study was to test the effects of the Mindfulness‐Based Stress Reduction (MBSR) intervention on depressive symptoms in patients with fibromyalgia. Methods This randomized controlled trial examined effects of the 8‐week MBSR intervention on depressive symptoms in 91 women with fibromyalgia who were randomly assigned to treatment (n = 51) or a waiting‐list control group (n = 40). Eligible patients were at least 18 years old, willing to participate in a weekly group, and able to provide physician verification of a fibromyalgia diagnosis. Of 166 eligible participants who responded to local television news publicizing, 49 did not appear for a scheduled intake, 24 enrolled but did not provide baseline data, and 2 were excluded due to severe mental illness, leaving 91 participants. The sample averaged 48 years of age and had 14.7 years of education. The typical participant was white, married, and employed. Patients randomly assigned to treatment received MBSR. Eight weekly 2.5‐hour sessions were led by a licensed clinical psychologist with mindfulness training. Somatic and cognitive symptoms of depression were assessed using the Beck Depression Inventory administered at baseline, immediately postprogram, and at followup 2 months after the conclusion of the intervention. Results Change in depressive symptoms was assessed using slopes analyses of intervention effects over time. Depressive symptoms improved significantly in treatment versus control participants over the 3 assessments. Conclusion This meditation‐based intervention alleviated depressive symptoms among patients with fibromyalgia.

<p>The practice of mindfulness is increasingly being integrated into contemporary clinical psychology. Based in Buddhist philosophy and subsequently integrated into Western health care in the contexts of psychotherapy and stress management, mindfulness meditation is evolving as a systematic clinical intervention. This article describes stress-reduction applications of mindfulness meditation predominantly in medical settings, as originally conceived and developed by Kabat-Zinn and colleagues. It describes process factors associated with the time-limited, group-based formal favored by this model, and presents in tabular form results of both early and more recent outcome studies.</p>

The practice of mindfulness is increasingly being integrated into contemporary clinical psychology. Based in Buddhist philosophy and subsequently integrated into Western health care in the contexts of psychotherapy and stress management, mindfulness meditation is evolving as a systematic clinical intervention. This article describes stress-reduction applications of mindfulness meditation predominantly in medical settings, as originally conceived and developed by Kabat-Zinn and colleagues. It describes process factors associated with the time-limited, group-based formal favored by this model, and presents in tabular form results of both early and more recent outcome studies.

This manuscript explores how one teacher educator worked to facilitate preservice teachers' (PSTs) learning across field- and university-based settings. Using socio-cultural learning theory as a lens, the analysis draws on case study data gathered for two PSTs from the same teacher education program (TEP), who experienced proximal, but considerably different student teaching placements in urban schools. Findings articulate the teacher educator's repertoire of moves as she worked to mediate PSTs' development as equity-minded, reflective practitioners. By examining the learner-centered and contextually sensitive aspects of teacher educator mediation, this manuscript challenges notions of "best practices" in teacher education and adds nuance to discussions about "rich" clinical experiences.

The recent diagnosis of the Anthropocene represents the public death of the modern understanding of Nature removed from society. It also challenges the modern science-politics settlement, where natural science speaks for a stable, objective Nature. This paper reviews recent efforts to develop ‘multinatural’ alternatives that provide an environmentalism that need not make recourse to Nature. Focusing on biodiversity conservation, the paper draws together work in the social and natural sciences to present an interdisciplinary biogeography for conservation in the Anthropocene. This approach is developed through an engagement with the critiques of neoliberal natures offered by political ecology.

RESEARCH QUESTION: Arthralgia affects postmenopausal breast cancer survivors (BCS) receiving aromatase inhibitors (AI), which may result in reduced function and long-term well-being. This is an exploratory, qualitative investigation of BCS who participated in a yoga-based program to understand impact on joint pain and various aspects of quality of life (QOL) through a yoga program.THEORETICAL FRAMEWORK: Social cognitive theory was used and provided the foundation for developing a yoga intervention through sources of efficacy information: (1) performance accomplishment, (2) structured experience, (3) verbal support from instructor and group, and (4) physical feedback. METHODOLOGY: Ten postmenopausal women with stage I-III breast cancer and AI associated arthralgia (AIAA) received yoga twice a week for eight weeks for 90 minutes and were instructed to continue in a home-based yoga program. We used social cognitive theory (SCT) to structure a yoga intervention as an ongoing physical activity to manage joint pain and function. Participants completed journal reflections on their experience and received weekly phone calls. ANALYSIS: Data was collected and analyzed using qualitative methods. Member checks were completed and emergent themes were explored and agreed upon by the research team to ensure reliability and validity of data. Several emergent themes were discovered: Empowerment: Importance of Camaraderie, Community, and Sharing; Pain Relief; Increased Physical Fitness (Energy, Flexibility, and Function); Relieved Stress/Anxiety and Transferability of Yoga through Breathing. These themes were identified through instructor observation, participant observation, and weekly phone call documentation. INTERPRETATION: Participants experienced an eight-week yoga intervention as an effective physical activity and support group that fostered various improvements in quality of life (QOL) and reduction in AIAA. Participants were highly motivated to improve physical fitness levels and reduce pain. This study revealed benefits from alternative forms of exercise such as yoga to provide a structure, which is transferable in other situations. Information, structured physical guidance in yoga postures, support, and feedback are necessary to foster physical activity for BCS experiencing pain. IMPLICATIONS FOR CANCER SURVIVORS: Results of this qualitative analysis indicate that interventions to support BCS with AIAA are warranted. Yoga appears to positively impact these side effects of hormonal therapies. Additional research would aid in the development of other interventions.

In Wildlife in the Anthropocene, Jamie Lorimer argues that the idea of nature as a pure and timeless place characterized by the absence of humans has come to an end. Offering a thorough appraisal of the Anthropocene—an era in which human actions affect and influence all life and all systems on our planet—Lorimer unpacks its implications for changing definitions of nature and the politics of wildlife conservation.

Elephants rarely breed in captivity and are not considered domesticated, yet they interact with people regularly and adapt to various environments. Too social and sagacious to be objects, too strange to be human, too captive to truly be wild, but too wild to be domesticated—where do elephants fall in our understanding of nature? In Wildlife in the Anthropocene, Jamie Lorimer argues that the idea of nature as a pure and timeless place characterized by the absence of humans has come to an end. But life goes on. Wildlife inhabits everywhere and is on the move; Lorimer proposes the concept of wildlife as a replacement for nature. Offering a thorough appraisal of the Anthropocene—an era in which human actions affect and influence all life and all systems on our planet— Lorimer unpacks its implications for changing definitions of nature and the politics of wildlife conservation. Wildlife in the Anthropocene examines rewilding, the impacts of wildlife films, human relationships with charismatic species, and urban wildlife. Analyzing scientific papers, policy documents, and popular media, as well as a decade of fieldwork, Lorimer explores the new interconnections between science, politics, and neoliberal capitalism that the Anthropocene demands of wildlife conservation. Imagining conservation in a world where humans are geological actors entangled within and responsible for powerful, unstable, and unpredictable planetary forces, this work nurtures a future environmentalism that is more hopeful and democratic.